In 1999, Larter began her film career with appearances in Varsity Blues and House on Haunted Hill. During the next few years, she appeared in a number of movies aimed at a teenage audience, including the box office successes Legally Blonde and Final Destination. In 2001, Larter performed in the stage play The Vagina Monologues in New York City.
As of October 2006, Larter is portraying Niki Sanders on the NBC TV series Heroes, and is scheduled to play Claire Redfield in Resident Evil: Extinction (2007).
Larter is a close friend of actress Amy Smart, with whom she co-starred in the film Varsity Blues. Larter has previously lived in Miami, Florida and currently lives in New York City, having moved there in the spring of 2002.
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